Aliskiren 

Aliskiren 

May 31, 2021
Aliskiren 

Where is Aliskiren used?

Aliskiren is a tablet medicine used in people with high blood pressure. Uncontrolled high blood pressure increases your risk of serious health problems such as stroke and heart attack.

This medicine belongs to the group known as direct renin inhibitors that relaxes blood vessels so blood can flow more easily. Controlling or lowering high blood pressure helps prevent kidney problems, heart attacks, and strokes.

 

How does Aliskiren work?

Aliskiren is an FDA-approved medication that acts on an enzyme in the body called renin. Usually, renin helps the body make a compound called angiotensin I. This is converted into angiotensin II as part of the body’s natural control of blood pressure. Angiotensin II causes blood vessels to constrict which increases the blood pressure. By blocking the action of renin, this medicine reduces the production of angiotensin I and II. This allows the blood vessels to relax and widen, which lowers blood pressure.

Lowering blood pressure within the whole population by lifestyle interventions such as increasing the consumption of fruit and vegetables or reducing dietary salt intake will be of great benefit. Also, blood pressure-lowering trials determine huge benefits in preventing heart failure, strokes, and coronary heart disease.

 

How is Aliskiren taken?

The dosage is based on your medical condition and response to the treatment. You should take this medication exactly as it is prescribed. Do not take more or less or more often than it is given by your doctor. Your doctor may start giving you a lower dose and gradually increase it.

Aliskiren is a medication to be taken by mouth, once a day, or as directed by your doctor. You may take each dose with or without a meal. Taking the medicine with a meal may help avoid or lessen nausea. High-fat foods may lessen how well this medicine is absorbed by the body. So, it is best to avoid taking this medication with a high-fat meal.

 

What are the precautions in taking Aliskiren?

  • Blood pressure-lowering medicines such as Aliskiren can sometimes make you feel dizzy or weary. You should avoid performing possibly dangerous tasks such as operating machinery or driving. If you feel dizzy, lie down for a few minutes or until the symptoms pass. If you frequently feel dizzy you must let your doctor know, your dose may need adjusting.
  • If you ever had an allergic reaction to this medication, let your doctor know. This drug may contain an inactive ingredient that may cause an allergic reaction.
  • Let your doctor know if you are taking any other medications including vitamins or herbal supplements.
  • Certain medicines should not be used during breastfeeding or pregnancy. However, other medicines may be safely used in breastfeeding or pregnancy providing the benefits to the mother outweighs the risks to the unborn baby. Let your doctor know if you are pregnant or planning a pregnancy, before using any medicine.
  • This medicine is not recommended for use in people with hereditary angioneurotic edema and severe kidney problems.
  • This medicine must be used carefully in people with diabetes, heart disease, fluid volume or low salt in the body, and liver disease.

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