March 22, 2021

Where is Acalabrutinib used?

Acalabrutinib is used for the cure of adult patients with mantle cell lymphoma (MCL). This is used for those who are having at least one prior therapy. Acalabrutinib is an inhibitor of Bruton tyrosine kinase that blocks a particular enzyme from working. This medicine can slow the development of cancer cells that is present. This has been already approved by the Food and Drug Administration (FDA).


How does Acalabrutinib work?

Acalabrutinib stops the activity of Bruton’s tyrosine kinase (BTK). It prevents the start of the B-cell antigen receptor (BCR) signaling way. This ends both B-cell activation and BTK-mediated and the activation of downstream survival pathways. Also, it leads to a reserve of the progress of fatal B cells that overexpress BTK.


How is Acalabrutinib taken?

The recommended dosage of this medication will depend on your medical condition, age, and response. This medication is to be taken by mouth. Each dose can be either taken with or without food.

Acalabrutinib is usually taken 2 times a day, 12 hours apart. Swallow the medicine as a whole with a glass of water. Do not break it. Follow your doctor’s instructions on time.

If you miss a dose of this medicine, take it as soon as you remember. If it is more than a few hours past your normal dosing time, avoid the missed dose and take your next dose at your regularly scheduled time. Do not take an extra dose to make up for a missed dose. It is important to take this prescription exactly as it is given by your doctor for the best results.


What are the precautions of taking Acalabrutinib?

  • If an allergic reaction happens, stop taking this medicine.
  • Do not use Acalabrutinib for any other treatment unless recommended by a doctor.
  • This may make you feel dizzy, avoid driving or using machinery.
  • Tell to your doctor if you are pregnant or planning to get pregnant.
  • Consult your doctor first before taking this if you have any current medication such as vitamins or herbal supplements.
  • Do not share your medicine with others who have the same conditions as yours.
  • This may increase your risk for skin cancer. For this reason, you need to limit your time in the sun.
  • This can make you more likely to get infections or may worsen any current infections.
  • Do not receive any immunizations or vaccinations without the consent of your doctor while you are taking this medication.
  • Your doctor must check your improvement at regular visits to make sure this medication is functioning correctly. To check for unwanted effects, you may also need a blood test.
  • Using this medication with other medicine is usually not recommended. However, in some cases, it may be unavoidable. If used together, your doctor may change how often you use this medicine or change the dose. Your doctor may also give you special instructions about the use of tobacco, alcohol, or food.
  • Do not expose this medicine to heat. Store at room temperature.
  • Keep this away and all your medicines away from the reach of children.

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